Zranb1 | zinc finger, RAN-binding domain containing 1

GeneMGI:106441Synonyms: D7Wsu87e, 9330160G10Rik

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Growth/size/body region Hematopoietic system Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Zranb1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased lean body mass	2 supporting datasets	Zranb1^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	4.99x10^-6
thrombocytosis	1 supporting dataset	Zranb1^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	1.73x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Zranb1.

Associated images

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Histopathology

There is no histopathology data found for Zranb1.

IMPC related publications

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External links

No external links available for Zranb1.

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*Zranb1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Zranb1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Zranb1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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