Atp5po | ATP synthase peripheral stalk subunit OSCP

GeneMGI:106341Synonyms: Atp5o, D12Wsu28e

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Mortality/aging

13 No significant impact

8 Not tested

Gene metrics:4Significant phenotypes
5Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetAtp5potm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
decreased grip strength1 supporting datasetAtp5potm1.1(KOMP)VlcgheterozygoteEarly adult4.52x10-6 
embryonic lethality prior to organogenesis1 supporting datasetAtp5potm1.1(KOMP)VlcghomozygoteE9.5N/A * 
improved glucose tolerance1 supporting datasetAtp5potm1.1(KOMP)VlcgheterozygoteEarly adult1.53x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Atp5potm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Atp5potm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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