Ilrun | inflammation and lipid regulator with UBA-like and NBR1-like domains

GeneMGI:106281Synonyms: D17Wsu92e

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Hematopoietic system Behavior/neurological

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



decreased startle reflex	1 supporting dataset	Ilrun^{Gt(IST12471H5)Tigm}	homozygote	Early adult	4.01x10^-6
abnormal uterus morphology	1 supporting dataset	Ilrun^{Gt(IST12471H5)Tigm}	homozygote	Early adult	N/A ^*
decreased lean body mass	2 supporting datasets	Ilrun^em1(IMPC)Tcp	homozygote	Early adult	3.93x10^-5
abnormal spleen morphology	2 supporting datasets	Ilrun^{Gt(IST12471H5)Tigm}	homozygote	Early adult	N/A ^*
small spleen	2 supporting datasets	Ilrun^{Gt(IST12471H5)Tigm}	homozygote	Early adult	N/A ^*
small seminal vesicle	1 supporting dataset	Ilrun^{Gt(IST12471H5)Tigm}	homozygote	Early adult	N/A ^*
small uterus	1 supporting dataset	Ilrun^{Gt(IST12471H5)Tigm}	homozygote	Early adult	N/A ^*
abnormal skin morphology	2 supporting datasets	Ilrun^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
impaired glucose tolerance	1 supporting dataset	Ilrun^em1(IMPC)Tcp	homozygote	Early adult	2.52x10^-7
increased spleen weight	1 supporting dataset	Ilrun^{Gt(IST12471H5)Tigm}	homozygote	Early adult	7.67x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ilrun.

Associated images

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Histopathology

There is no histopathology data found for Ilrun.

IMPC related publications

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External links

No external links available for Ilrun.

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*Ilrun^{Gt(IST12471H5)Tigm}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ilrun^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Ilrun^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ilrun^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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