Ccr2 | C-C motif chemokine receptor 2
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Immune system Growth/size/body region Muscle Hematopoietic system Behavior/neurological Cardiovascular system
13 No significant impact
5 Not tested
Data collections
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal heart left ventricle morphology | 4 supporting datasets | Ccr2em1(IMPC)H | homozygote | Late adult | 3.33x10-7 | ||
| decreased neutrophil cell number | 1 supporting dataset | Ccr2em1(IMPC)H | homozygote | Late adult | 3.73x10-8 | ||
| increased cardiac muscle contractility | 1 supporting dataset | Ccr2em1(IMPC)H | homozygote | Late adult | 1.11x10-5 | ||
| decreased monocyte cell number | 1 supporting dataset | Ccr2em1(IMPC)H | homozygote | Late adult | 2.51x10-11 | ||
| enlarged heart | 1 supporting dataset | Ccr2em1(IMPC)H | homozygote | Late adult | N/A * | ||
| abnormal gait | 1 supporting dataset | Ccr2em1(IMPC)H | homozygote | Early adult | 9.89x10-5 | ||
| increased eosinophil cell number | 2 supporting datasets | Ccr2em1(IMPC)H | homozygote | Late adult | 2.95x10-21 | ||
| decreased lymphocyte cell number | 1 supporting dataset | Ccr2em1(IMPC)H | homozygote | Late adult | 1.24x10-5 |
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External links
No external links available for Ccr2.
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| Ccr2em1(IMPC)H | Intra-exon deletion | | mouse |