Etfb | electron transferring flavoprotein, beta polypeptide

GeneMGI:106098Synonyms: 0610009I16Rik, 2810441H06Rik

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Immune system Growth/size/body region Nervous system Vision/eye Hematopoietic system Mortality/aging Cardiovascular system

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal retina morphology1 supporting datasetEtfbem1(IMPC)HmguheterozygoteEarly adult1.46x10-6 
preweaning lethality, complete penetrance1 supporting datasetEtfbem1(IMPC)HmguhomozygoteEarly adultN/A * 
abnormal optic disk morphology1 supporting datasetEtfbem1(IMPC)HmguheterozygoteEarly adult6.03x10-5 
persistence of hyaloid vascular system1 supporting datasetEtfbem1(IMPC)HmguheterozygoteEarly adult1.1x10-6 
increased heart weight1 supporting datasetEtfbem1(IMPC)HmguheterozygoteEarly adult1.82x10-6 
abnormal retina vasculature morphology1 supporting datasetEtfbem1(IMPC)HmguheterozygoteEarly adult1.79x10-9 
increased spleen weight1 supporting datasetEtfbem1(IMPC)HmguheterozygoteEarly adult8.74x10-15 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Etfbem1(IMPC)HmguIntra-exon deletionmouse
Etfbtm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Etfbtm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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