Mki67 | antigen identified by monoclonal antibody Ki 67

GeneMGI:106035Synonyms: D630048A14Rik, Ki-67, +1 more

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Immune system Integument Hematopoietic system

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased mean corpuscular hemoglobin	1 supporting dataset	Mki67^em1(IMPC)Mbp	homozygote	Early adult	1.58x10^-12
decreased lymphocyte cell number	2 supporting datasets	Mki67^em1(IMPC)Mbp	homozygote	Early adult	2.69x10^-9
abnormal skin morphology	1 supporting dataset	Mki67^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased erythrocyte cell number	1 supporting dataset	Mki67^em1(IMPC)Mbp	homozygote	Early adult	1.66x10^-12
increased eosinophil cell number	1 supporting dataset	Mki67^em1(IMPC)Mbp	homozygote	Early adult	7.65x10^-10
increased mean corpuscular volume	1 supporting dataset	Mki67^em1(IMPC)Mbp	homozygote	Early adult	1.4x10^-35
increased neutrophil cell number	1 supporting dataset	Mki67^em1(IMPC)Mbp	homozygote	Early adult	3.09x10^-7
increased red blood cell distribution width	1 supporting dataset	Mki67^em1(IMPC)Mbp	homozygote	Early adult	4.11x10^-23
decreased leukocyte cell number	1 supporting dataset	Mki67^em1(IMPC)Mbp	homozygote	Early adult	8.61x10^-5
increased basophil cell number	1 supporting dataset	Mki67^em1(IMPC)Mbp	homozygote	Early adult	9.56x10^-10

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mki67.

Associated images

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Histopathology

There is no histopathology data found for Mki67.

IMPC related publications

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External links

No external links available for Mki67.

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*Mki67^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Mki67^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mki67^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Mki67^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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