Tkt | transketolase

GeneMGI:105992Synonyms: p68

Physiological systems

10 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Hematopoietic system Mortality/aging

8 No significant impact

14 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic lethality prior to tooth bud stage	1 supporting dataset	Tkt^em1(IMPC)H	homozygote	E12.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Tkt^em1(IMPC)H	homozygote	Early adult	N/A ^*
increased red blood cell distribution width	1 supporting dataset	Tkt^em1(IMPC)H	heterozygote	Early adult	7.14x10^-6
embryonic lethality prior to organogenesis	1 supporting dataset	Tkt^em1(IMPC)H	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tkt.

Associated images

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Histopathology

There is no histopathology data found for Tkt.

IMPC related publications

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External links

No external links available for Tkt.

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*Tkt^em1(IMPC)H*	Exon Deletion	‌	mouse
*Tkt^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Tkt^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Tkt^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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