Adam26a | ADAM metallopeptidase domain 26A

GeneMGI:105985Synonyms: Adam26, Dtgn4

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Respiratory system

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal epididymis morphology	1 supporting dataset	Adam26a^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
enlarged epididymis	1 supporting dataset	Adam26a^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
decreased bronchoconstrictive response	3 supporting datasets	Adam26a^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.8x10^-7
small testis	1 supporting dataset	Adam26a^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Adam26a^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Adam26a.

Associated images

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Histopathology

There is no histopathology data found for Adam26a.

IMPC related publications

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External links

No external links available for Adam26a.

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*Adam26a^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Adam26a^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Adam26a^{tm115750(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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