Cfb | complement factor B
Physiological systems
22 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Renal/urinary system
19 No significant impact
2 Not tested
Data collections
Gene metrics:6Significant phenotypes
4Associated diseases
Expression examined in:52Adult tissues
50Embryo tissues
| increased hematocrit | 1 supporting dataset | Cfbtm1.1(KOMP)Wtsi | homozygote | Early adult | 1.78x10-5 | ||
| increased erythrocyte cell number | 1 supporting dataset | Cfbtm1.1(KOMP)Wtsi | homozygote | Early adult | 5.06x10-9 | ||
| abnormal kidney morphology | 1 supporting dataset | Cfbtm1.1(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| decreased circulating phosphate level | 1 supporting dataset | Cfbtm1.1(KOMP)Wtsi | homozygote | Early adult | 4.91x10-6 | ||
| increased fasting circulating glucose level | 1 supporting dataset | Cfbtm1.1(KOMP)Wtsi | homozygote | Early adult | 3.2x10-7 | ||
| increased hemoglobin content | 1 supporting dataset | Cfbtm1.1(KOMP)Wtsi | homozygote | Early adult | 1.12x10-8 |
| | | | | | | | | | |
| adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
| aorta | heterozygote | n/a | 0% (0/2) | 0.19% (1/533) |
| bone | heterozygote | n/a | 0% (0/2) | 0% (0/394) |
| bone marrow | heterozygote | n/a | 0% (0/2) | 0% (0/22) |
| brain | heterozygote | n/a | 0% (0/2) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | 0% (0/2) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | 0% (0/2) | 0.22% (1/454) |
| cerebellum | heterozygote | n/a | 0% (0/2) | 0.56% (3/532) |
| cerebral cortex | heterozygote | n/a | 0% (0/2) | 0.41% (2/491) |
External links
No external links available for Cfb.
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| Cfbtm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Cfbtm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell mouse |
| Cfbtm1.1(KOMP)Wtsi | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Cfbtm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Cfbtm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Cfbtm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Cfbtm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |