Txlna | taxilin alpha

GeneMGI:105968Synonyms: 2600010N21Rik, IL14, +1 more

Physiological systems

18 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Hematopoietic system Behavior/neurological Mortality/aging

11 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



small testis	1 supporting dataset	Txlna^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased large unstained cell number	1 supporting dataset	Txlna^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.56x10^-5
decreased exploration in new environment	1 supporting dataset	Txlna^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.41x10^-7
increased lymphocyte cell number	1 supporting dataset	Txlna^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.94x10^-5
decreased hemoglobin content	1 supporting dataset	Txlna^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.71x10^-7
increased large unstained cell number	1 supporting dataset	Txlna^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.02x10^-6
preweaning lethality, incomplete penetrance	1 supporting dataset	Txlna^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
abnormal gait	1 supporting dataset	Txlna^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.91x10^-5
increased circulating potassium level	1 supporting dataset	Txlna^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.45x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Txlna.

Associated images

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Histopathology

There is no histopathology data found for Txlna.

IMPC related publications

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External links

No external links available for Txlna.

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*Txlna^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Txlna^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Txlna^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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