Mpp1 | membrane protein, palmitoylated

GeneMGI:105941Synonyms: p55, erythrocyte protein p55, +2 more

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Growth/size/body region Vision/eye Respiratory system Hematopoietic system

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased T-helper cell number	1 supporting dataset	Mpp1^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.35x10^-6
enlarged lymph nodes	1 supporting dataset	Mpp1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased CD4-positive, alpha-beta T cell number	1 supporting dataset	Mpp1^{em1(IMPC)Ccpcz}	homozygote	Early adult	6.52x10^-6
abnormal eye morphology	1 supporting dataset	Mpp1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal lymph node morphology	1 supporting dataset	Mpp1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
anophthalmia	1 supporting dataset	Mpp1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased effector memory T-helper cell number	1 supporting dataset	Mpp1^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.66x10^-5
enlarged spleen	1 supporting dataset	Mpp1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased effector memory T-helper cell number	1 supporting dataset	Mpp1^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.42x10^-5
decreased lung elastance	1 supporting dataset	Mpp1^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.56x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mpp1.

Associated images

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Histopathology

There is no histopathology data found for Mpp1.

IMPC related publications

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External links

No external links available for Mpp1.

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*Mpp1^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Mpp1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mpp1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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