Cfi | complement component factor i

GeneMGI:105937

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Behavior/neurological

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

8Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



thrombocytopenia	1 supporting dataset	Cfi^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.6x10^-6
decreased locomotor activity	1 supporting dataset	Cfi^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.28x10^-8
increased circulating alanine transaminase level	1 supporting dataset	Cfi^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.36x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cfi.

Associated images

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Histopathology

There is no histopathology data found for Cfi.

IMPC related publications

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External links

No external links available for Cfi.

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*Cfi^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Cfi^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Cfi^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Cfi^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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