Rab3ip | RAB3A interacting protein

GeneMGI:105933Synonyms: Rabin3, SSX2 interacting protein, +1 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

13 No significant impact

6 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

decreased bone mineral density1 supporting datasetRab3iptm1.1(KOMP)VlcghomozygoteEarly adult8.44x10-9 
abnormal bone structure1 supporting datasetRab3iptm1.1(KOMP)VlcghomozygoteEarly adult1x10-6 
increased mean corpuscular volume1 supporting datasetRab3iptm1.1(KOMP)VlcghomozygoteEarly adult1.39x10-5 
decreased exploration in new environment1 supporting datasetRab3iptm1.1(KOMP)VlcghomozygoteEarly adult7.82x10-5 
increased mean corpuscular hemoglobin1 supporting datasetRab3iptm1.1(KOMP)VlcghomozygoteEarly adult6.89x10-7 
increased circulating alkaline phosphatase level1 supporting datasetRab3iptm1.1(KOMP)VlcghomozygoteEarly adult1.04x10-5 
increased lean body mass1 supporting datasetRab3iptm1.1(KOMP)VlcghomozygoteEarly adult7.88x10-5 
decreased bone mineral content1 supporting datasetRab3iptm1.1(KOMP)VlcghomozygoteEarly adult2.28x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rab3iptm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Rab3iptm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Rab3iptm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Rab3iptm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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