Slc1a1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1

GeneMGI:105083Synonyms: EAAC1, EAAT3, +2 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Behavior/neurological

15 No significant impact

6 Not tested

Gene metrics:5Significant phenotypes
4Associated diseases
Expression examined in:48Adult tissues
46Embryo tissues

Phenotypes

increased vertical activity1 supporting datasetSlc1a1tm1b(KOMP)WtsihomozygoteEarly adult2.26x10-5 
increased exploration in new environment1 supporting datasetSlc1a1tm1b(KOMP)WtsihomozygoteEarly adult1.68x10-5 
fused cornea and lens1 supporting datasetSlc1a1tm1b(KOMP)WtsihomozygoteEarly adult7.42x10-5 
increased circulating iron level1 supporting datasetSlc1a1tm1b(KOMP)WtsihomozygoteEarly adult1.61x10-7 
increased circulating sodium level1 supporting datasetSlc1a1tm1b(KOMP)WtsihomozygoteEarly adult2.89x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Slc1a1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Slc1a1tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Slc1a1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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