Ssr1 | signal sequence receptor, alpha

GeneMGI:105082Synonyms: TRAPalpha, SSR

Physiological systems

22 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Integument Endocrine/exocrine gland Embryo Growth/size/body region Vision/eye Liver/biliary system Mortality/aging Cardiovascular system Renal/urinary system

11 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:17Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



edema	1 supporting dataset	Ssr1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
microphthalmia	1 supporting dataset	Ssr1^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	Ssr1^em1(IMPC)Mbp	heterozygote	Early adult	1.63x10^-5
small kidney	1 supporting dataset	Ssr1^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Ssr1^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal placenta vasculature	1 supporting dataset	Ssr1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal placenta size	1 supporting dataset	Ssr1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
abnormal blood vessel morphology	1 supporting dataset	Ssr1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
cataract	1 supporting dataset	Ssr1^em1(IMPC)Mbp	heterozygote	Early adult	1.36x10^-5
abnormal placenta morphology	1 supporting dataset	Ssr1^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ssr1.

Associated images

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Histopathology

There is no histopathology data found for Ssr1.

IMPC related publications

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External links

No external links available for Ssr1.

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*Ssr1^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Ssr1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ssr1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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