Slc9a4 | solute carrier family 9 (sodium/hydrogen exchanger), member 4

GeneMGI:105074Synonyms: NHE4, D730009J23Rik

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Nervous system Behavior/neurological Skeleton

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



decreased bone mineral density	1 supporting dataset	Slc9a4^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.16x10^-10
decreased prepulse inhibition	1 supporting dataset	Slc9a4^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.91x10^-5
increased circulating cholesterol level	1 supporting dataset	Slc9a4^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	9.9x10^-5
decreased startle reflex	1 supporting dataset	Slc9a4^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.41x10^-6
decreased bone mineral content	2 supporting datasets	Slc9a4^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.78x10^-12

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Slc9a4.

Associated images

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Histopathology

There is no histopathology data found for Slc9a4.

IMPC related publications

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External links

No external links available for Slc9a4.

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*Slc9a4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Slc9a4^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

My Genes