Cobl | cordon-bleu WH2 repeat

GeneMGI:105056Synonyms: C530045F18Rik

Physiological systems

22 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Cardiovascular system

17 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged thymus1 supporting datasetCoblem1(IMPC)CcpczhomozygoteEarly adultN/A * 
increased effector memory T-helper cell number1 supporting datasetCoblem1(IMPC)CcpczhomozygoteEarly adult4.25x10-5 
abnormal thymus morphology1 supporting datasetCoblem1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged heart1 supporting datasetCoblem1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal heart morphology1 supporting datasetCoblem1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Coblem1(IMPC)CcpczExon Deletionmouse
Cobltm191774(pL1L2_GT0_DelLacZ_bsd)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Cobltm191774(pL1L2_frt_BetactP_neo_frt_lox)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Cobltm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Cobltm1e(KOMP)WtsiTargeted, non-conditional allelees cell

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