Mxd4 | Max dimerization protein 4

GeneMGI:104991Synonyms: bHLHc12, Mad4, +1 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Cardiovascular system

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating alkaline phosphatase level	1 supporting dataset	Mxd4^em1(IMPC)J	homozygote	Early adult	9.25x10^-20
increased circulating calcium level	1 supporting dataset	Mxd4^em1(IMPC)J	homozygote	Early adult	4.55x10^-5
prolonged QRS complex duration	1 supporting dataset	Mxd4^em1(IMPC)J	homozygote	Early adult	2.04x10^-5
increased leukocyte cell number	1 supporting dataset	Mxd4^em1(IMPC)J	homozygote	Early adult	1.05x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mxd4.

Associated images

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Histopathology

There is no histopathology data found for Mxd4.

IMPC related publications

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External links

No external links available for Mxd4.

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*Mxd4^em1(IMPC)J*	Exon Deletion	‌	mouse
*Mxd4^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mxd4^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Mxd4^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mxd4^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Mxd4^{tm45050(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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