Cyp7b1 | cytochrome P450, family 7, subfamily b, polypeptide 1

GeneMGI:104978Synonyms: hct-1, D3Ertd552e

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

4Associated diseases

Expression examined in:51Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased total retina thickness	1 supporting dataset	Cyp7b1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	1.66x10^-5
impaired glucose tolerance	1 supporting dataset	Cyp7b1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.47x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cyp7b1.

Associated images

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Histopathology

There is no histopathology data found for Cyp7b1.

IMPC related publications

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External links

No external links available for Cyp7b1.

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*Cyp7b1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Cyp7b1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Cyp7b1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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