Glg1 | golgi apparatus protein 1
Physiological systems
17 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Skeleton Mortality/aging
14 No significant impact
7 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Glg1tm1a(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| increased circulating glycerol level | 1 supporting dataset | Glg1tm1a(KOMP)Wtsi | heterozygote | Early adult | 8.29x10-5 | ||
| abnormal vertebral arch morphology | 1 supporting dataset | Glg1tm1a(KOMP)Wtsi | heterozygote | Early adult | 4.87x10-5 | ||
| increased circulating triglyceride level | 1 supporting dataset | Glg1tm1a(KOMP)Wtsi | heterozygote | Early adult | 8.03x10-5 |
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Human diseases caused by Glg1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Glg1.
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| Glg1tm192253(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Glg1tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |