Syt17 | synaptotagmin XVII
Physiological systems
21 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Limbs/digits/tail Respiratory system Hematopoietic system Skeleton
16 No significant impact
3 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
| decreased pulmonary ventilation | 3 supporting datasets | Syt17tm1b(KOMP)Wtsi | homozygote | Early adult | 1.27x10-6 | ||
| increased circulating serum albumin level | 1 supporting dataset | Syt17tm1b(KOMP)Wtsi | homozygote | Early adult | 1.38x10-15 | ||
| increased mean corpuscular volume | 1 supporting dataset | Syt17tm1b(KOMP)Wtsi | homozygote | Early adult | 5.39x10-5 | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Syt17tm1b(KOMP)Wtsi | homozygote | Early adult | 3.87x10-11 | ||
| increased pulmonary respiratory rate | 1 supporting dataset | Syt17tm1b(KOMP)Wtsi | homozygote | Early adult | 4.87x10-5 | ||
| increased circulating calcium level | 1 supporting dataset | Syt17tm1b(KOMP)Wtsi | homozygote | Early adult | 1.98x10-12 | ||
| increased circulating total protein level | 1 supporting dataset | Syt17tm1b(KOMP)Wtsi | homozygote | Early adult | 2.24x10-12 | ||
| increased blood urea nitrogen level | 1 supporting dataset | Syt17tm1b(KOMP)Wtsi | homozygote | Early adult | 5.27x10-7 | ||
| short tibia | 1 supporting dataset | Syt17tm1b(KOMP)Wtsi | homozygote | Early adult | 2.3x10-5 |
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| adrenal gland | heterozygote | Section images Wholemount images | 75% (3/4) | 0.7% (4/570) |
| aorta | heterozygote | n/a | 0% (0/4) | 0.19% (1/533) |
| blood | heterozygote | n/a | 0% (0/2) | 0% (0/17) |
| bone marrow | heterozygote | n/a | 0% (0/2) | 0% (0/22) |
| brain | heterozygote | Wholemount images | 100% (4/4) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | n/a | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/4) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | n/a | 0.22% (1/454) |
| cecum | heterozygote | n/a | 50% (2/4) | 7.75% (22/284) |
| cerebellum | heterozygote | n/a | 0% (0/4) | 0.56% (3/532) |
External links
No external links available for Syt17.
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| Syt17tm1(EGFP_CreERT2)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Syt17tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Syt17tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Syt17tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Syt17tm82985(L1L2_Pgk_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |