Syt17 | synaptotagmin XVII

GeneMGI:104966Synonyms: Bk

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Limbs/digits/tail Respiratory system Hematopoietic system Skeleton

16 No significant impact

3 Not tested

Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

decreased pulmonary ventilation3 supporting datasetsSyt17tm1b(KOMP)WtsihomozygoteEarly adult1.27x10-6 
increased circulating serum albumin level1 supporting datasetSyt17tm1b(KOMP)WtsihomozygoteEarly adult1.38x10-15 
increased mean corpuscular volume1 supporting datasetSyt17tm1b(KOMP)WtsihomozygoteEarly adult5.39x10-5 
increased circulating alkaline phosphatase level1 supporting datasetSyt17tm1b(KOMP)WtsihomozygoteEarly adult3.87x10-11 
increased pulmonary respiratory rate1 supporting datasetSyt17tm1b(KOMP)WtsihomozygoteEarly adult4.87x10-5 
increased circulating calcium level1 supporting datasetSyt17tm1b(KOMP)WtsihomozygoteEarly adult1.98x10-12 
increased circulating total protein level1 supporting datasetSyt17tm1b(KOMP)WtsihomozygoteEarly adult2.24x10-12 
increased blood urea nitrogen level1 supporting datasetSyt17tm1b(KOMP)WtsihomozygoteEarly adult5.27x10-7 
short tibia1 supporting datasetSyt17tm1b(KOMP)WtsihomozygoteEarly adult2.3x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Syt17tm1(EGFP_CreERT2)WtsiReporter-tagged deletion allele (with selection cassette)ES Cell
Syt17tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Syt17tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Syt17tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Syt17tm82985(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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