Gpcpd1 | glycerophosphocholine phosphodiesterase 1

GeneMGI:104898Synonyms: 2310004G06Rik, Prei4, +1 more

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Integument Nervous system Skeleton Mortality/aging

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	3 supporting datasets	Gpcpd1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Gpcpd1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
abnormal skin morphology	2 supporting datasets	Gpcpd1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
abnormal cholesterol homeostasis	1 supporting dataset	Gpcpd1^em1(IMPC)Tcp	heterozygote	Early adult	6.21x10^-5
abnormal sternum morphology	1 supporting dataset	Gpcpd1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
decreased circulating serum albumin level	1 supporting dataset	Gpcpd1^em1(IMPC)Tcp	heterozygote	Early adult	8.15x10^-5
decreased circulating calcium level	1 supporting dataset	Gpcpd1^em1(IMPC)Tcp	heterozygote	Early adult	6.75x10^-5
decreased circulating creatinine level	1 supporting dataset	Gpcpd1^em1(IMPC)Tcp	heterozygote	Early adult	5.65x10^-5
decreased prepulse inhibition	1 supporting dataset	Gpcpd1^em1(IMPC)Tcp	heterozygote	Early adult	1.78x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gpcpd1.

Associated images

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Histopathology

There is no histopathology data found for Gpcpd1.

IMPC related publications

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External links

No external links available for Gpcpd1.

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*Gpcpd1^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Gpcpd1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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