Pdia4 | protein disulfide isomerase associated 4

GeneMGI:104864Synonyms: ERp72, U48620, +2 more

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

17 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes



increased circulating aspartate transaminase level	1 supporting dataset	Pdia4^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.92x10^-5
increased circulating creatine kinase level	1 supporting dataset	Pdia4^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.2x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pdia4.

Associated images

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Histopathology

There is no histopathology data found for Pdia4.

IMPC related publications

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External links

No external links available for Pdia4.

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*Pdia4^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Pdia4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pdia4^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Pdia4^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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