Pls3 | plastin 3 (T-isoform)

GeneMGI:104807Synonyms: T-fimbrin

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Behavior/neurological

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased circulating alkaline phosphatase level	1 supporting dataset	Pls3^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.13x10^-5
increased mean corpuscular hemoglobin	1 supporting dataset	Pls3^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.29x10^-5
increased circulating triglyceride level	1 supporting dataset	Pls3^{tm1a(EUCOMM)Wtsi}	hemizygote	Early adult	1.98x10^-6
increased grip strength	2 supporting datasets	Pls3^{tm1a(EUCOMM)Wtsi}	hemizygote	Early adult	1.19x10^-5
increased circulating phosphate level	1 supporting dataset	Pls3^{tm1a(EUCOMM)Wtsi}	hemizygote	Early adult	3.29x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pls3.

Associated images

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Histopathology

There is no histopathology data found for Pls3.

IMPC related publications

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External links

No external links available for Pls3.

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*Pls3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pls3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pls3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Pls3^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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