Kcnj6 | potassium inwardly-rectifying channel, subfamily J, member 6

GeneMGI:104781Synonyms: GIRK2, KCNJ7, +1 more

Physiological systems

14 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

12 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

hyperactivity8 supporting datasetsKcnj6em1(IMPC)HhomozygoteEarly adult1.07x10-15 
impaired righting response1 supporting datasetKcnj6em1(IMPC)HhomozygoteEarly adult3.49x10-8 
increased exploration in new environment1 supporting datasetKcnj6em1(IMPC)HhomozygoteEarly adult6.63x10-5 
decreased anxiety-related response1 supporting datasetKcnj6em1(IMPC)HhomozygoteEarly adult1.57x10-8 
increased circulating amylase level1 supporting datasetKcnj6em1(IMPC)HhomozygoteEarly adult8.18x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Kcnj6em1(IMPC)HIntra-exon deletionmouse
Kcnj6em2(IMPC)HIntra-exon deletionmouse
Kcnj6em3(IMPC)HIntra-exon deletionmouse
Kcnj6tm212573(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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