Prkdc | protein kinase, DNA activated, catalytic polypeptide
Physiological systems
16 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Hematopoietic system
13 No significant impact
8 Not tested
Data collections
Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased eosinophil cell number | 1 supporting dataset | Prkdcem2(IMPC)Ics | homozygote | Early adult | 6.47x10-10 | ||
| increased neutrophil cell number | 1 supporting dataset | Prkdcem2(IMPC)Ics | homozygote | Early adult | 2.02x10-29 | ||
| decreased lymphocyte cell number | 2 supporting datasets | Prkdcem2(IMPC)Ics | homozygote | Early adult | 1.31x10-46 | ||
| decreased leukocyte cell number | 1 supporting dataset | Prkdcem2(IMPC)Ics | homozygote | Early adult | 1.33x10-16 | ||
| increased circulating phosphate level | 1 supporting dataset | Prkdcem2(IMPC)Ics | homozygote | Early adult | 3.71x10-6 | ||
| increased monocyte cell number | 1 supporting dataset | Prkdcem2(IMPC)Ics | homozygote | Early adult | 1.19x10-8 | ||
| decreased mean corpuscular hemoglobin concentration | 1 supporting dataset | Prkdcem2(IMPC)Ics | homozygote | Early adult | 3.71x10-7 |
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External links
No external links available for Prkdc.
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| Prkdcem2(IMPC)Ics | Exon Deletion | | mouse |