Kcnj3 | potassium inwardly-rectifying channel, subfamily J, member 3

GeneMGI:104742Synonyms: Kcnf3, Kir3.1, +1 more

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Respiratory system Behavior/neurological Mortality/aging

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

1Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased pulmonary ventilation	3 supporting datasets	Kcnj3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.23x10^-5
hyperactivity	5 supporting datasets	Kcnj3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	7.93x10^-7
decreased thigmotaxis	2 supporting datasets	Kcnj3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	5.29x10^-9
decreased pulmonary respiratory rate	1 supporting dataset	Kcnj3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.56x10^-5
limb grasping	1 supporting dataset	Kcnj3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.32x10^-7
preweaning lethality, incomplete penetrance	1 supporting dataset	Kcnj3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased pulmonary ventilation	1 supporting dataset	Kcnj3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.07x10^-6
abnormal behavior	1 supporting dataset	Kcnj3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	5.3x10^-9
increased respiratory quotient	1 supporting dataset	Kcnj3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.07x10^-12
abnormal epididymis morphology	1 supporting dataset	Kcnj3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Kcnj3.

Associated images

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Histopathology

There is no histopathology data found for Kcnj3.

IMPC related publications

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External links

No external links available for Kcnj3.

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*Kcnj3^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Kcnj3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Kcnj3^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

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