Cct3 | chaperonin containing TCP1 subunit 3
Physiological systems
18 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Hematopoietic system Behavior/neurological Mortality/aging Cardiovascular system
14 No significant impact
6 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
decreased mean corpuscular hemoglobin | 1 supporting dataset | Cct3em1(IMPC)Tcp | heterozygote | Early adult | 5.48x10-6 | ||
increased startle reflex | 1 supporting dataset | Cct3em1(IMPC)Tcp | heterozygote | Early adult | 1.49x10-8 | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Cct3em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
increased mean platelet volume | 1 supporting dataset | Cct3em1(IMPC)Tcp | heterozygote | Early adult | 3.06x10-30 | ||
embryonic lethality prior to organogenesis | 1 supporting dataset | Cct3em1(IMPC)Tcp | homozygote | E9.5 | N/A * | ||
prolonged QT interval | 1 supporting dataset | Cct3em1(IMPC)Tcp | heterozygote | Early adult | 6.42x10-5 | ||
decreased exploration in new environment | 1 supporting dataset | Cct3em1(IMPC)Tcp | heterozygote | Early adult | 9.27x10-6 |
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External links
No external links available for Cct3.
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Cct3em1(IMPC)Tcp | Exon Deletion | | mouse |
Cct3tm119383(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |