Scnn1b | sodium channel, nonvoltage-gated 1 beta
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Skeleton Mortality/aging
17 No significant impact
4 Not tested
Gene metrics:3Significant phenotypes
6Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
abnormal pelvic girdle bone morphology | 1 supporting dataset | Scnn1btm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.25x10-5 | ||
increased circulating fructosamine level | 1 supporting dataset | Scnn1btm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.06x10-5 | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Scnn1btm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * |
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External links
No external links available for Scnn1b.
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Scnn1btm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Scnn1btm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Scnn1btm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |