Hgs | HGF-regulated tyrosine kinase substrate

GeneMGI:104681Synonyms: tn, Hrs

Physiological systems

23 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Behavior/neurological Mortality/aging

21 No significant impact

1 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Hgs^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Hgs^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal behavior	2 supporting datasets	Hgs^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.61x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hgs.

Associated images

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Histopathology

There is no histopathology data found for Hgs.

IMPC related publications

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External links

No external links available for Hgs.

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*Hgs^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Hgs^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Hgs^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Hgs^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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