Tfap2b | transcription factor AP-2 beta

GeneMGI:104672Synonyms: AP-2(beta), Tcfap2b, +1 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Nervous system Vision/eye Behavior/neurological Mortality/aging

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



iris synechia	1 supporting dataset	Tfap2b^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	1.41x10^-5
increased grip strength	2 supporting datasets	Tfap2b^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	3.18x10^-12
abnormal optic disk morphology	1 supporting dataset	Tfap2b^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	8.46x10^-9
preweaning lethality, complete penetrance	1 supporting dataset	Tfap2b^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Tfap2b.

Associated images

Loading...

Histopathology

There is no histopathology data found for Tfap2b.

IMPC related publications

Loading...

External links

No external links available for Tfap2b.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Tfap2b^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Tfap2b^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

My Genes