Fkbp5 | FK506 binding protein 5
Physiological systems
22 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Immune system Growth/size/body region Vision/eye Hematopoietic system Mortality/aging Renal/urinary system
16 No significant impact
2 Not tested
Data collections
Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:73Adult tissues
50Embryo tissues
| increased lean body mass | 1 supporting dataset | Fkbp5tm1b(KOMP)Wtsi | heterozygote | Early adult | 3.31x10-5 | ||
| increased kidney weight | 2 supporting datasets | Fkbp5tm1b(KOMP)Wtsi | homozygote | Early adult | 1.49x10-5 | ||
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Fkbp5tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| increased neutrophil cell number | 1 supporting dataset | Fkbp5tm1b(KOMP)Wtsi | homozygote | Early adult | 1.23x10-6 | ||
| increased basophil cell number | 1 supporting dataset | Fkbp5tm1b(KOMP)Wtsi | homozygote | Early adult | 1.34x10-9 | ||
| increased kidney weight | 1 supporting dataset | Fkbp5tm1b(KOMP)Wtsi | heterozygote | Early adult | 7.39x10-5 | ||
| cornea opacity | 1 supporting dataset | Fkbp5tm1b(KOMP)Wtsi | homozygote | Early adult | 8.7x10-5 |
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External links
No external links available for Fkbp5.
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| Fkbp5tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Fkbp5tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Fkbp5tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |