Tle1 | transducin-like enhancer of split 1

GeneMGI:104636Synonyms: Tle4l, Grg1, +2 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Mortality/aging

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Tle1^{em1(IMPC)Hmgu}	homozygote	Early adult	N/A ^*
decreased total retina thickness	1 supporting dataset	Tle1^{em1(IMPC)Hmgu}	homozygote	Early adult	1.77x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tle1.

Associated images

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Histopathology

There is no histopathology data found for Tle1.

IMPC related publications

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External links

No external links available for Tle1.

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*Tle1^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse
*Tle1^{tm264408(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Tle1^{tm50693(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Tle1^{tm50693(L1L2_gt2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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