Fgd1 | FYVE, RhoGEF and PH domain containing 1

GeneMGI:104566Synonyms: ZFYVE3, faciogenital dysplasia

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Endocrine/exocrine gland Embryo Growth/size/body region Vision/eye Hematopoietic system Craniofacial

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal embryo size	1 supporting dataset	Fgd1^em1(IMPC)Tcp	hemizygote	E15.5	N/A ^*
abnormal craniofacial morphology	1 supporting dataset	Fgd1^em1(IMPC)Tcp	heterozygote	E15.5	N/A ^*
microphthalmia	1 supporting dataset	Fgd1^em1(IMPC)Tcp	hemizygote	E15.5	N/A ^*
edema	1 supporting dataset	Fgd1^em1(IMPC)Tcp	hemizygote	E15.5	N/A ^*
abnormal craniofacial morphology	1 supporting dataset	Fgd1^em1(IMPC)Tcp	hemizygote	E15.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Fgd1^em1(IMPC)Tcp	hemizygote	E15.5	N/A ^*
enlarged thymus	1 supporting dataset	Fgd1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fgd1.

Associated images

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Histopathology

There is no histopathology data found for Fgd1.

IMPC related publications

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External links

No external links available for Fgd1.

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*Fgd1^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Fgd1^{tm47889(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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