Cdkn1b | cyclin dependent kinase inhibitor 1B
Physiological systems
17 / 24 physiological systems tested
9 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Growth/size/body region Nervous system Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system
8 No significant impact
7 Not tested
Data collections
Gene metrics:14Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased spleen weight | 1 supporting dataset | Cdkn1bem2(IMPC)H | homozygote | Early adult | 1.81x10-15 | ||
| increased fasting circulating glucose level | 1 supporting dataset | Cdkn1bem2(IMPC)H | homozygote | Early adult | 2.29x10-10 | ||
| decreased bone mineral density | 1 supporting dataset | Cdkn1bem2(IMPC)H | homozygote | Early adult | 2.57x10-7 | ||
| abnormal retina morphology | 1 supporting dataset | Cdkn1bem2(IMPC)H | homozygote | Early adult | 1.15x10-16 | ||
| decreased bone mineral content | 1 supporting dataset | Cdkn1bem2(IMPC)H | homozygote | Early adult | 7.57x10-5 | ||
| decreased mean corpuscular hemoglobin | 1 supporting dataset | Cdkn1bem2(IMPC)H | homozygote | Early adult | 1.26x10-7 | ||
| abnormal optic disk morphology | 1 supporting dataset | Cdkn1bem2(IMPC)H | homozygote | Early adult | 8.03x10-6 | ||
| abnormal startle reflex | 1 supporting dataset | Cdkn1bem2(IMPC)H | homozygote | Early adult | 3.47x10-5 | ||
| decreased monocyte cell number | 1 supporting dataset | Cdkn1bem2(IMPC)H | homozygote | Early adult | 8.7x10-5 | ||
| decreased circulating triglyceride level | 1 supporting dataset | Cdkn1bem2(IMPC)H | homozygote | Early adult | 2.87x10-7 |
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External links
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| Cdkn1bem2(IMPC)H | Indel | | mouse |