Napb | N-ethylmaleimide sensitive fusion protein attachment protein beta

GeneMGI:104562Synonyms: b-SNAP, I47, +3 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased anxiety-related response1 supporting datasetNapbtm1b(EUCOMM)HmguheterozygoteEarly adult1.71x10-5 
decreased thigmotaxis2 supporting datasetsNapbtm1b(EUCOMM)HmguheterozygoteEarly adult1.71x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetNapbtm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
hyperactivity1 supporting datasetNapbtm1b(EUCOMM)HmguheterozygoteEarly adult5.16x10-5 
abnormal behavior1 supporting datasetNapbtm1b(EUCOMM)HmguheterozygoteEarly adult1.71x10-5 
decreased grip strength2 supporting datasetsNapbtm1b(EUCOMM)HmguheterozygoteEarly adult7.11x10-5 
decreased locomotor activity1 supporting datasetNapbtm1b(EUCOMM)HmguheterozygoteEarly adult2.02x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Napbtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Napbtm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Napbtm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Napbtm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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