Nsf | N-ethylmaleimide sensitive fusion protein
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Hematopoietic system Behavior/neurological Mortality/aging
14 No significant impact
5 Not tested
Data collections
Gene metrics:8Significant phenotypes
1Associated diseases
Expression examined in:49Adult tissues
29Embryo tissues
| decreased thigmotaxis | 2 supporting datasets | Nsftm1b(KOMP)Mbp | heterozygote | Early adult | 9.5x10-5 | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Nsftm1b(KOMP)Mbp | homozygote | E12.5 | N/A * | ||
| decreased circulating glucose level | 1 supporting dataset | Nsftm1b(KOMP)Mbp | heterozygote | Early adult | 1.15x10-6 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Nsftm1b(KOMP)Mbp | homozygote | E9.5 | N/A * | ||
| abnormal retina morphology | 1 supporting dataset | Nsftm1b(KOMP)Mbp | heterozygote | Early adult | 2.79x10-5 | ||
| decreased circulating HDL cholesterol level | 1 supporting dataset | Nsftm1b(KOMP)Mbp | heterozygote | Early adult | 4.01x10-8 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Nsftm1b(KOMP)Mbp | homozygote | Early adult | N/A * | ||
| increased hemoglobin content | 1 supporting dataset | Nsftm1b(KOMP)Mbp | heterozygote | Early adult | 3.08x10-6 |
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External links
No external links available for Nsf.
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| Nsftm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Nsftm1b(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Nsftm1e(KOMP)Mbp | Targeted, non-conditional allele | | ES Cell |