Rcn1 | reticulocalbin 1

GeneMGI:104559Synonyms: Rcn

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Limbs/digits/tail Vision/eye Skeleton Cardiovascular system

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating alkaline phosphatase level	1 supporting dataset	Rcn1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.03x10^-10
persistence of hyaloid vascular system	1 supporting dataset	Rcn1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.54x10^-6
abnormal retina vasculature morphology	1 supporting dataset	Rcn1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.24x10^-10
abnormal retina morphology	1 supporting dataset	Rcn1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.13x10^-7
short tibia	1 supporting dataset	Rcn1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.89x10^-6
abnormal lens morphology	1 supporting dataset	Rcn1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.4x10^-5
abnormal retina blood vessel morphology	1 supporting dataset	Rcn1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.59x10^-9
decreased blood urea nitrogen level	1 supporting dataset	Rcn1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	8.61x10^-5
cataract	1 supporting dataset	Rcn1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.77x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rcn1.

Associated images

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Histopathology

There is no histopathology data found for Rcn1.

IMPC related publications

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External links

No external links available for Rcn1.

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*Rcn1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Rcn1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Rcn1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Rcn1^{tm40194(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Rcn1^{tm40194(L1L2_st1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Rcn1^{tm40194(L1L2_st2)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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