Rhbdf1 | rhomboid 5 homolog 1

GeneMGI:104328Synonyms: Dist1, Egfr-rs, +1 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Behavior/neurological Skeleton Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased bone mineral density	1 supporting dataset	Rhbdf1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	8.25x10^-6
preweaning lethality, incomplete penetrance	1 supporting dataset	Rhbdf1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased grip strength	1 supporting dataset	Rhbdf1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	2.26x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rhbdf1.

Associated images

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Histopathology

There is no histopathology data found for Rhbdf1.

IMPC related publications

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External links

No external links available for Rhbdf1.

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*Rhbdf1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Rhbdf1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Rhbdf1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Rhbdf1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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