Tiam1 | T cell lymphoma invasion and metastasis 1

GeneMGI:103306Synonyms: D16Ium10, D16Ium10e

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Behavior/neurological

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased cornea thickness	1 supporting dataset	Tiam1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	9.96x10^-5
decreased exploration in new environment	1 supporting dataset	Tiam1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.07x10^-9
decreased locomotor activity	1 supporting dataset	Tiam1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	4.65x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tiam1.

Associated images

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Histopathology

There is no histopathology data found for Tiam1.

IMPC related publications

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External links

No external links available for Tiam1.

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*Tiam1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Tiam1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Tiam1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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