Polr1c | polymerase (RNA) I polypeptide C
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Pigmentation Integument Vision/eye Behavior/neurological Mortality/aging
12 No significant impact
7 Not tested
Data collections
Gene metrics:8Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| impaired righting response | 1 supporting dataset | Polr1cem1(IMPC)J | heterozygote | Late adult | 2.36x10-7 | ||
| abnormal coat/ hair morphology | 1 supporting dataset | Polr1cem1(IMPC)J | heterozygote | Late adult | 3.8x10-5 | ||
| absent vibrissae | 1 supporting dataset | Polr1cem1(IMPC)J | heterozygote | Late adult | 1.32x10-5 | ||
| cataract | 1 supporting dataset | Polr1cem1(IMPC)J | heterozygote | Early adult | 5.55x10-5 | ||
| abnormal coat/hair pigmentation | 2 supporting datasets | Polr1cem1(IMPC)J | heterozygote | Late adult | 7.44x10-9 | ||
| limb grasping | 1 supporting dataset | Polr1cem1(IMPC)J | heterozygote | Late adult | 6.81x10-8 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Polr1cem1(IMPC)J | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Polr1cem1(IMPC)J | homozygote | Early adult | N/A * |
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External links
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| Polr1cem1(IMPC)J | Exon Deletion | | mouse |
| Polr1ctm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Polr1ctm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |