Atp6v0a1 | ATPase, H+ transporting, lysosomal V0 subunit A1
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Adipose tissue Skeleton Mortality/aging
15 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
29Embryo tissues
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Atp6v0a1tm1b(EUCOMM)Hmgu | homozygote | E12.5 | N/A * | ||
| increased circulating potassium level | 1 supporting dataset | Atp6v0a1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 3.1x10-18 | ||
| increased bone mineral content | 1 supporting dataset | Atp6v0a1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.93x10-5 | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Atp6v0a1tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Atp6v0a1tm1b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
| decreased total body fat amount | 2 supporting datasets | Atp6v0a1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 8.52x10-7 |
| | | | | | | | | | |
External links
No external links available for Atp6v0a1.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Atp6v0a1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Atp6v0a1tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Atp6v0a1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |