Slk | STE20-like kinase

GeneMGI:103241Synonyms: 9A2, Etk4, +3 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Embryo Growth/size/body region Behavior/neurological Mortality/aging

14 No significant impact

6 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal embryo size1 supporting datasetSlkem1(IMPC)BayheterozygoteE9.5N/A * 
increased vertical activity1 supporting datasetSlkem1(IMPC)BayheterozygoteEarly adult6.37x10-8 
embryonic growth retardation1 supporting datasetSlkem1(IMPC)BayheterozygoteE9.5N/A * 
preweaning lethality, complete penetrance2 supporting datasetsSlkem1(IMPC)BayhomozygoteEarly adultN/A * 
hyperactivity1 supporting datasetSlkem1(IMPC)BayheterozygoteEarly adult2.7x10-5 
prenatal lethality1 supporting datasetSlkem1(IMPC)BayhomozygoteE18.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Slkem1(IMPC)BayExon Deletionmouse
Slktm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Slktm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Slktm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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