Tfap4 | transcription factor AP4

GeneMGI:103239Synonyms: D930048N17Rik, Tcfap4, +2 more

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Adipose tissue Growth/size/body region Hematopoietic system Skeleton Mortality/aging Cardiovascular system

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased total body fat amount	1 supporting dataset	Tfap4^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.59x10^-5
increased red blood cell distribution width	1 supporting dataset	Tfap4^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	5.45x10^-5
increased mean corpuscular volume	1 supporting dataset	Tfap4^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	5.87x10^-6
prolonged RR interval	1 supporting dataset	Tfap4^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	3.85x10^-8
increased lean body mass	1 supporting dataset	Tfap4^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.58x10^-5
abnormal sacral vertebrae morphology	1 supporting dataset	Tfap4^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	7.79x10^-12
abnormal uterus morphology	1 supporting dataset	Tfap4^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
decreased heart rate	1 supporting dataset	Tfap4^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.81x10^-7
abnormal lumbar vertebrae morphology	1 supporting dataset	Tfap4^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	7.79x10^-12
enlarged heart	1 supporting dataset	Tfap4^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Tfap4.

Associated images

Loading...

Histopathology

There is no histopathology data found for Tfap4.

IMPC related publications

Loading...

External links

No external links available for Tfap4.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Tfap4^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Tfap4^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Tfap4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Tfap4^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes