Cox7c | cytochrome c oxidase subunit 7C

GeneMGI:103226Synonyms: Cox7c1, COXVIIc

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Embryo Growth/size/body region Limbs/digits/tail Mortality/aging

14 No significant impact

4 Not tested

Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
46Embryo tissues

Phenotypes

increased fasting circulating glucose level1 supporting datasetCox7ctm1b(KOMP)MbpheterozygoteEarly adult2.19x10-6 
abnormal placenta size1 supporting datasetCox7ctm1b(KOMP)MbphomozygoteE15.5N/A * 
abnormal embryo size1 supporting datasetCox7ctm1b(KOMP)MbphomozygoteE15.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetCox7ctm1b(KOMP)MbphomozygoteEarly adultN/A * 
prenatal lethality1 supporting datasetCox7ctm1b(KOMP)MbphomozygoteE18.5N/A * 
abnormal skin coloration1 supporting datasetCox7ctm1b(KOMP)MbphomozygoteE15.5N/A * 
embryonic growth retardation1 supporting datasetCox7ctm1b(KOMP)MbphomozygoteE12.5N/A * 
abnormal placenta development1 supporting datasetCox7ctm1b(KOMP)MbphomozygoteE12.5N/A * 
abnormal limb bud morphology1 supporting datasetCox7ctm1b(KOMP)MbphomozygoteE12.5N/A * 
abnormal placenta size1 supporting datasetCox7ctm1b(KOMP)MbphomozygoteE12.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cox7ctm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Cox7ctm1b(KOMP)MbpReporter-tagged deletion allele (with selection cassette)mouse

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