Cyp4b1 | cytochrome P450, family 4, subfamily b, polypeptide 1
GeneMGI:103225
Physiological systems
18 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological Cardiovascular system
15 No significant impact
6 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:70Adult tissues
0Embryo tissues
| increased exploration in new environment | 1 supporting dataset | Cyp4b1tm1b(KOMP)Wtsi | homozygote | Early adult | 7.8x10-6 | ||
| increased fasting circulating glucose level | 1 supporting dataset | Cyp4b1tm1b(KOMP)Wtsi | homozygote | Early adult | 2.08x10-5 | ||
| decreased blood urea nitrogen level | 1 supporting dataset | Cyp4b1tm1b(KOMP)Wtsi | homozygote | Early adult | 8.91x10-7 | ||
| shortened PR interval | 1 supporting dataset | Cyp4b1tm1b(KOMP)Wtsi | homozygote | Early adult | 4.84x10-5 | ||
| increased circulating bilirubin level | 1 supporting dataset | Cyp4b1tm1b(KOMP)Wtsi | homozygote | Early adult | 5.77x10-6 | ||
| increased circulating aspartate transaminase level | 1 supporting dataset | Cyp4b1tm1b(KOMP)Wtsi | homozygote | Early adult | 1.22x10-7 | ||
| decreased circulating triglyceride level | 1 supporting dataset | Cyp4b1tm1b(KOMP)Wtsi | homozygote | Early adult | 9.51x10-9 |
| | | | | | | | | | |
External links
No external links available for Cyp4b1.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Cyp4b1tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Cyp4b1tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Cyp4b1tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | es cell |