Zbtb16 | zinc finger and BTB domain containing 16

GeneMGI:103222Synonyms: Zfp145, Green's luxoid, +1 more

Physiological systems

20 / 24 physiological systems tested

12 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Adipose tissue Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Liver/biliary system Hearing/vestibular/ear Hematopoietic system Behavior/neurological

8 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:23Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



hyperactivity	6 supporting datasets	Zbtb16^em1(IMPC)Mbp	homozygote	Early adult	5.51x10^-10
abnormal spleen morphology	1 supporting dataset	Zbtb16^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Zbtb16^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal optic disk morphology	1 supporting dataset	Zbtb16^em1(IMPC)Mbp	homozygote	Early adult	2.22x10^-9
small spleen	1 supporting dataset	Zbtb16^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal gait	1 supporting dataset	Zbtb16^em1(IMPC)Mbp	homozygote	Early adult	2.09x10^-20
abnormal brain morphology	2 supporting datasets	Zbtb16^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal liver morphology	2 supporting datasets	Zbtb16^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small liver	2 supporting datasets	Zbtb16^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal autopod morphology	1 supporting dataset	Zbtb16^em1(IMPC)Mbp	homozygote	Early adult	1.14x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Zbtb16.

Associated images

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Histopathology

There is no histopathology data found for Zbtb16.

IMPC related publications

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External links

No external links available for Zbtb16.

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*Zbtb16^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Zbtb16^{tm405544(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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