Zbtb16 | zinc finger and BTB domain containing 16
Physiological systems
20 / 24 physiological systems tested
12 Significantly impacted by the knock-out
Reproductive system Immune system Endocrine/exocrine gland Adipose tissue Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Liver/biliary system Hearing/vestibular/ear Hematopoietic system Behavior/neurological
8 No significant impact
4 Not tested
Data collections
Gene metrics:23Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| hyperactivity | 6 supporting datasets | Zbtb16em1(IMPC)Mbp | homozygote | Early adult | 5.51x10-10 | ||
| abnormal spleen morphology | 1 supporting dataset | Zbtb16em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal testis morphology | 1 supporting dataset | Zbtb16em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal optic disk morphology | 1 supporting dataset | Zbtb16em1(IMPC)Mbp | homozygote | Early adult | 2.22x10-9 | ||
| small spleen | 1 supporting dataset | Zbtb16em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal gait | 1 supporting dataset | Zbtb16em1(IMPC)Mbp | homozygote | Early adult | 2.09x10-20 | ||
| abnormal brain morphology | 2 supporting datasets | Zbtb16em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal liver morphology | 2 supporting datasets | Zbtb16em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| small liver | 2 supporting datasets | Zbtb16em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal autopod morphology | 1 supporting dataset | Zbtb16em1(IMPC)Mbp | homozygote | Early adult | 1.14x10-7 |
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Human diseases caused by Zbtb16 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Zbtb16.
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| Zbtb16em1(IMPC)Mbp | Exon Deletion | | mouse |
| Zbtb16tm405544(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |