Dsc2 | desmocollin 2

GeneMGI:103221Synonyms: Dsc2b, Dsc2a

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Cardiovascular system

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



cornea opacity	1 supporting dataset	Dsc2^{tm1e(KOMP)Wtsi}	homozygote	Early adult	2.07x10^-15
cornea vascularization	1 supporting dataset	Dsc2^{tm1e(KOMP)Wtsi}	homozygote	Early adult	5.76x10^-17
narrow eye opening	1 supporting dataset	Dsc2^{tm1e(KOMP)Wtsi}	homozygote	Early adult	7.71x10^-5
abnormal cornea morphology	1 supporting dataset	Dsc2^{tm1e(KOMP)Wtsi}	homozygote	Early adult	6.6x10^-12

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dsc2.

Associated images

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Histopathology

There is no histopathology data found for Dsc2.

IMPC related publications

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External links

No external links available for Dsc2.

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*Dsc2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Dsc2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell mouse
*Dsc2^{tm44818(L1L2_st0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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