Mpz | myelin protein zero

GeneMGI:103177Synonyms: Mpp, P0

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Nervous system Respiratory system Hematopoietic system Behavior/neurological

12 No significant impact

6 Not tested

Gene metrics:9Significant phenotypes
15Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal lung morphology1 supporting datasetMpzem1(IMPC)TcphomozygoteEarly adultN/A * 
increased mean platelet volume1 supporting datasetMpzem1(IMPC)TcphomozygoteEarly adult5.49x10-5 
abnormal skin morphology1 supporting datasetMpzem1(IMPC)TcphomozygoteEarly adultN/A * 
tremors1 supporting datasetMpzem1(IMPC)TcphomozygoteEarly adult2x10-19 
decreased grip strength2 supporting datasetsMpzem1(IMPC)TcphomozygoteEarly adult1.33x10-9 
decreased prepulse inhibition1 supporting datasetMpzem1(IMPC)TcphomozygoteEarly adult4.36x10-5 
decreased locomotor activity2 supporting datasetsMpzem1(IMPC)TcphomozygoteEarly adult3.9x10-6 
decreased fasting circulating glucose level1 supporting datasetMpzem1(IMPC)TcphomozygoteEarly adult2.37x10-6 
abnormal gait1 supporting datasetMpzem1(IMPC)TcphomozygoteEarly adult2x10-19 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Mpzem1(IMPC)TcpIndelmouse

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter