Dync1h1 | dynein cytoplasmic 1 heavy chain 1

GeneMGI:103147Synonyms: Dnec1, dynein heavy chain, retrograde transport, +5 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
6Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal vocalization1 supporting datasetDync1h1tm1dIcsheterozygoteEarly adult2.45x10-5 
decreased locomotor activity1 supporting datasetDync1h1tm1dIcsheterozygoteEarly adult8.8x10-6 
impaired glucose tolerance1 supporting datasetDync1h1tm1dIcsheterozygoteEarly adult1.28x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dync1h1tm182983(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Dync1h1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Dync1h1tm1aIcsKO first allele (reporter-tagged insertion with conditional potential)ES Cell
mouse
Dync1h1tm1dIcsDeletion allele (post-Flp and Cre with no reporter)mouse

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